ePrescribing
Architected for real-time
electronic PA.
Designed from the ground up for NCPDP SCRIPT integration and Surescripts connectivity, with FHIR-ready architecture for the 2027 CMS mandate. ePa isn't a bolt-on — the architecture is built for it.
Architecture
Designed for complete ePa integration
Full Transaction Coverage
Architected to support the complete NCPDP SCRIPT transaction set: InitiationRequest, InitiationResponse, Appeal, RxChangeRequest, CancelRx, and more.
Surescripts-Ready
Designed for real-time message exchange with the national ePrescribing network. No batch delays when live.
ePa Operations Dashboard
Built-in monitoring for transaction volumes, response times, error rates, and compliance status — ready for when ePa goes live.
FHIR-Ready Architecture
Built ahead of the 2027 CMS mandate. NexusLedge accepts FHIR requests and fulfills them via NCPDP SCRIPT in production — the 2027 standard delivered via today’s reality. PBMs commit to the mandate now, not in 2027.
NCPDP SCRIPT
Native Protocol
FHIR-Ready
Architecture
2027
CMS Mandate Ready
100%
Audit-Ready
"The ePa mandate isn't coming as a surprise. PBMs that build toward it now — rather than retrofitting in 2026 — will be the ones positioned when CMS writes the next rule. The architecture question has to be answered before the deadline, not on it."
Explore the Platform
ePrescribing across the platform
Prior Authorization
Full lifecycle management
ePa integrates with the full PA pipeline — intake to determination.
AI Capabilities
Clinical AI intelligence
AI assessment runs on every PA request regardless of submission channel.
Regulatory Agility
Days, not quarters
Regulatory changes become platform capabilities before the deadline, not after.
See how NexusLedge is built for ePa
Request a demo to see FHIR-ready ePa architecture in your workflow context.
See the Platform